Creative Biostructure, with expertise in protein chemistry, analytical chemistry and functional assays, recently released custom hydrophobic interaction chromatography service to deliver efficient and cost-effective solutions in protein purification.

 

Hydrophobic Interaction Chromatography (HIC) is a chromatographic method that separates and purifies biological macromolecules based on their hydrophobicity differences, similar to reversed phase chromatography (RPC). HIC is commonly used as a useful supplement to other purification methods. It is an excellent next step method for samples separated by ion-exchange chromatography (IEX) or ammonium sulfate precipitation, which is typically used for initial sample concentration and clean-up. In both cases, the sample has a high salt concentration, which means it can be applied directly to the HIC medium without or with little preparation. HIC can be used at any stage of the purification process, including the capture, intermediate, and polishing stages.

 

Custom hydrophobic interaction chromatography is now available from Creative Biostructure for advanced biological macromolecule separation and purification. There are various experimental systems available from AKTA and Bio-Rad. The company also offers a variety of HIC medium to its customers to meet various needs. With years of experience, science team at Creative Biostructure will consider the structure of target molecules as well as reversible hydrophobic interactions. By doing this, Creative Biostructure establishes the optimal HIC strategy for each individual case to meet diversified requirements.

 

Other chromatography and purification services are also available at Creative Biostructure, including but not limited to: Affinity Chromatography, Ion-exchange Chromatography, Size-Exclusion Chromatography, Reversed Phase Chromatography, TFF/Diafiltration, etc.

 

“Furthermore, we undertake the development of challenging proteins, such as co-expression or assembly of higher-order complexes. After purification, protein analysis services including characterization, interaction, engineering, and structural determination are available at Creative Biostructure for your choice.” Commented Joanna, the chief marketing staff at Creative Biostructure.

 

To know more detailed information about the hydrophobic interaction chromatography services newly released by Creative Biostructure, please visit https://www.creative-biostructure.com/custom-hydrophobic-interaction-chromatography-service-260.htm.